To test the effects of two Mediterranean diet (MedDiet) interventions versus a low-fat diet on incidence of diabetes.
Three participant groups, one in the MedDiet with olive oil group, one on the MedDiet with nuts group, and the control group. When the two MedDiet groups were pooled and compared with the control group, diabetes incidence was reduced by 52% (27–86). In all study arms, increased adherence to the MedDiet was inversely associated with diabetes incidence. Diabetes risk reduction occurred in the absence of significant changes in body weight or physical activity.
MedDiets without calorie restriction seem to be effective in the prevention of diabetes in subjects at high cardiovascular risk.
Reduction in the Incidence of Type 2 Diabetes With the Mediterranean Diet: Results of the PREDIMED-Reus nutrition intervention randomized trial
Corresponding author: Jordi Salas-Salvadó, firstname.lastname@example.org.